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Victor Michael Aquino, MD $$

Pediatric Hematologist/Oncologist

Professor at UT Southwestern Medical Center

Languages Spoken:
English Spanish

Locations

UT Southwestern Pediatric Group

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Biography

Victor Aquino, M.D., is a hematologist and oncologist at Children’s Health℠ who specializes in pediatric bone marrow transplantation for children with cancer and blood disorders. He is also a professor of pediatrics at UT Southwestern Medical Center.

After receiving his medical degree and completing a pediatric residency at State University of New York, Dr. Aquino performed his pediatric hematology and oncology fellowship training at UT Southwestern and Children’s Medical Center.

Dr. Aquino is an active investigator in the Children’s Oncology Group, an international research organization supported by the National Cancer Institute. Through his research, Dr. Aquino seeks to improve supportive care of children undergoing hematopoietic stem cell transplantation.

Additionally, Dr. Aquino’s research interests include transplant for children with immunodeficiency syndromes as well as prevention and treatment of infections in pediatric patients going through hematopoietic stem cell transplantation.

In his free time, Dr. Aquino enjoys running and spending time with his family.

Education and Training

Medical School
State University of New York (SUNY) at Syracuse (1989)
Residency
SUNY Upstate Medical University (1992), Pediatrics
Fellowship
UT Southwestern - Children's Medical Center (1995), Hematology & Oncology
Board Certification
American Board of Pediatrics/Hematology-Oncology

Conditions

  • Immunodeficiency

  • Research Interests

    • Development of stem cell transplant protocols for children with malignant and non-malignant disorders
    • Development of treatment strategies to manage the complications of stem cell transplant and chemotherapy
    • Management of bacterial and fungal infections in children with malignancies
    • Outpatient management of febrile neutropenia in selected patients with cancer
    • Phase I and II trials of new chemotherapeutic agents in children with cancer

  • Publications

    • Transplantation of severe combined immunodeficiency in 240 patients from 2000-2009: A report from the Primary Immune Deficiency Treatment Consortium of North America. Pai SY, Logan B,  Griffith LM, Buckley RH,  Parrott RS, Dvorak CC, Neena Kapoor, Hanson IC, Filipovich AH,  Sullivan K, Small TN, Burroughs L, Haight A,  Pulsipher M, Chan K, Fuleihan R, Haddad E, Loechelt B, Aquino VM, Gillio A, Davis J, Knutsen A, Smith A, Moore T, Schroeder M, Goldman F, Connelly J, Porteus M, Xiang Q,2 Shearer WT, Thomas Fleisher TA, Kohn DB, Puck J, Notarangelo LD, Cowan MJ, O’Reilly RJ. New England Journal of Medicine. 371(5):434-46, 2014 Jul 31.
    • Safety and efficacy of intravenous pentamidine in children and adolescents undergoing hematopoietic stem cell transplantation. DeMasi J, Cox J, Koh A, and Aquino VM. Pediatric Infectious Disease Journal. 2013
    • The diagnostic value of Interleukin-5 and Monocyte Chemotactic Protein in risk stratification of febrile neutropenic pediatric oncology patients. Journal of Pediatric Hematology/Oncology. Aquino VM, Gomez A, Bowers DC, Ramilo O, Slone T, Hoffman T, Ahmad N, Winick N, and Leavey PJ.  J Pediatr Hematol Oncol. 2012
    • Unrelated donor cord blood transplantation for children with severe sickle cell disease: Results of one cohort from the phase II study from the Blood And Marrow Transplant Clinical Trials Network. Kamani N, Wlaters N, Carter S, Aquino VM, Brochstein Ha, Chaudhury S, Eapen M, Freed Bm, Grimley M, Levine Je, Logan B, Moore R, Panepinto J, Parikh, S, Pulsipher Ma, Sande J, Shultz Kr, Spellmen S, and Shenoy S. Biol Blood Marrow Transplant. 2012
    • The diagnostic utility of routine chest radiography in the evaluation of the initial fever in patients undergoing hematopoietic stem cell transplantation. Cox JA, DeMasi, J, McCollum S, Jackson G, Scothorn D, and Aquino VM. Pediatr Blood Cancer 2011
    • Oral ciprofloxacin in the outpatient management of children with cancer with febril neutropenia at low risk of bacteremia., Aquino VM, Herrera L, Sandler ES, Buchanan GR Cancer 2000 88 1710-1714
    • Evaluation of thymic output by measurement of T-cell-receptor gene rearrangement excisional circles (TREC) in patients who have received fludarabine, Aquino VM, Douek DC, Berryman B, Johnson M, Jain V, Collins RH Leukemia and Lymphoma 2003 44 343-348
    • A prospective double blind randomized trial of urokinase flushes to prevent bacteremia due to luminal colonization of central venous catheters., Aquino VM, Sandler ES, Mustafa MM, Steele J, Buchanan GR J Pediatr Hematol Oncol 2002 24 710-713
    • Clinical parameters associated with low bacteremia risk in 1100 pediatric oncology patients with fever and neutropenia, Baorto EP,Aquino VM, Mullen CA, Buchanan GR Cancer 2001 92 909-913
    • Oral ciprofloxacin in the outpatient management of children with cancer with febril neutropenia at low risk of bacteremia., Aquino VM, Herrera L, Sandler ES, Buchanan GR Cancer 2000 88 1710-1714
    • A phase II study of carboplatin in the treatment of low grade optic gliomas., Aquino VM, Fort D, Kamen B Journal of Neuro-Oncology 1999 41 255-259
    • New England Journal of Medicine. Pai SY, Logan B,  Griffith LM, Buckley RH,  Parrott RS, Dvorak CC, Neena Kapoor, Hanson IC, Filipovich AH,  Sullivan K, Small TN, Burroughs L, Haight A,  Pulsipher M, Chan K, Fuleihan R, Haddad E, Loechelt B, Aquino VM, Gillio A, Davis J, Knutsen A, Smith A, Moore T, Schroeder M, Goldman F, Connelly J, Porteus M, Xiang Q,2 Shearer WT, Thomas Fleisher TA, Kohn DB, Puck J, Notarangelo LD, Cowan MJ, O’Reilly RJ. Transplantation of severe combined immunodeficiency in 240 patients from 2000-2009: A report from the Primary Immune Deficiency Treatment Consortium of North America. 371(5):434-46, 2014 Jul 31.
    • Journal of Pediatric Hematology/OncologyAquino VM, Gomez A, Bowers DC, Ramilo O, Slone T, Hoffman T, Ahmad N, Winick N, and Leavey PJ.  The diagnostic value of Interleukin-5 and Monocyte Chemotactic Protein in risk stratification of febrile neutropenic pediatric oncology patients.. J Pediatr Hematol Oncol. 2012;34(6):e241-5.
    • Biol Blood Marrow Transplant Kamani N, Wlaters N, Carter S, Aquino VM, Brochstein Ha, Chaudhury S, Eapen M, Freed Bm, Grimley M, Levine Je, Logan B, Moore R, Panepinto J, Parikh, S, Pulsipher Ma, Sande J, Shultz Kr, Spellmen S, and Shenoy S. Unrelated donor cord blood transplantation for children with severe sickle cell disease: Results of one cohort from the phase II study from the Blood And Marrow Transplant Clinical Trials Network.. 2012;18:1265-72.
    • The PLADO Trial, A Transfusion Medicine/Hemostasis Clinical Trials Network Study Slichter SJ, Kaufman R, Assmann SF, McCullough J, Triulzi DJ, Strauss RG, Gernsheimer TB, Ness PM, Brecher ME, Josephson CD, Konkle BA, Woodson RD, Ortel TL, Hillyer CD, Skerrett DL, McCrae KR, Sloan SR, Uhl L, George JN, Aquino VM, Manno C, McFarland JG, Hess JR, Leissinger C, and Granger S. Effects of platelet dose on transfusion outcomes N Engl J Med 2010; 362:600-613.
    • Almatrafi MA, Aquino VM, Slone T, Huang R, Sebert M. Community Airborne Mold Spore Counts and Invasive Fungal Disease Risk Among Pediatric Hematological Malignancy and Stem Cell Transplant Patients. Open Forum Infect Dis. 2021 Sep 25;8(11):ofab481. doi: 10.1093/ofid/ofab481. PMID: 34805427; PMCID: PMC8597966.
    • Marsh RA, Hebert K, Kim S, Dvorak CC, Aquino VM, Baker KS, Chellapandian D, Dávila Saldaña B, Duncan CN, Eckrich MJ, Georges GE, Olson TS, Pulsipher MA, Shenoy S, Stenger E, Lugt MV, Yu LC, Gennery AR, Eapen M. Comparison of hematopoietic cell transplant conditioning regimens for hemophagocytic lymphohistiocytosis disorders. J Allergy Clin Immunol. 2021 Aug 8:S0091-6749(21)01205-7.
    • Goldberg J, Bender J, Jeha S, Sulis ML, Gardner R, Pollard, J, Aquino, V, Laetsch T, Winick, N, Fu C,  Marcus L, Sun W, Verma A, Burke M, Ho P, Manley T, Mody R, Oesterheld, J, Tcheng W, Thomson, B, Park, J, Sposto, R, Messinger, Y, Hijiya,N, Gaynon, P, Barredo, J. A Phase I Study Of Panobinostat in children with relapsed and refractory hematologic malignancies. Pediatr Hematol Oncol. 2020 Sep;37(6):465-74
    • Dandoy CE; Kelley T; Gaur AH, Nagarajan R, Demmel K, Badia P, Guinipero T, Hakim H, Owings A, Myers K, Aquino V, Oldridge C, Rae ML, Schjodt K, Kilcrease T, Scurlock M, Marshburn AM, Hill M, Langevin M, Lee J, Cooksey R, Mian A, Eckles S, Ferrell J, El-Bietar J, Nelson A, Turpin B, Huang FS, Lawlor J, Esporas M, Lane A, Hord J, Billett AL. Outcomes after bloodstream infection in hospitalized pediatric hematology/oncology and stem cell transplant patients. Pediatr Blood Cancer. 2019 Dec;66(12):e27978
    • Pai SY, Logan B,  Griffith LM, Buckley RH,  Parrott RS, Dvorak CC, Neena Kapoor, Hanson IC, Filipovich AH,  Sullivan K, Small TN, Burroughs L, Haight A,  Pulsipher M, Chan K, Fuleihan R, Haddad E, Loechelt B, Aquino VM, Gillio A, Davis J, Knutsen A, Smith A, Moore T, Schroeder M, Goldman F, Connelly J, Porteus M, Xiang Q,2 Shearer WT, Thomas Fleisher TA, Kohn DB, Puck J, Notarangelo LD, Cowan MJ, O’Reilly RJ. Transplantation of severe combined immunodeficiency in 240 patients from 2000-2009: A report from the Primary Immune Deficiency Treatment Consortium of North America. New England Journal of Medicine. 371(5):434-46, 2014 Jul 31

  • Professional Activities

    • American Academy of Pediatrics (1989)
    • American Society of Clinical Oncology (1996)
    • American Society of Hematology (1997)
    • Children's Oncology Group
    • Dallas County Medical Society and Texas Medical Association (1996)
    • Society of Pediatric Research (2002)

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