Dubin-Johnson syndrome in children

What is Dubin-Johnson syndrome in children?

Dubin-Johnson syndrome, also know as Dubin-Sprinz syndrome, is when someone older than a newborn develops jaundice (a yellow caste of the skin and whites of the eyes). Jaundice is a fairly common condition that affects otherwise healthy newborn babies. However, Dubin-Johnson syndrome usually appears in adolescence (12-17 years of age) or early adulthood.

Risk factors

Dubin-Johnson syndrome seems to most frequently affect Jewish Iranian and Moroccan people living in Israel, as well as Japanese people. However, it can affect people of any ethnic background.

What are the signs and symptoms of Dubin-Johnson syndrome in children?

• Jaundice 

• Muscle weakness

• Nausea and/or vomiting

• Pain in the upper abdomen

What are the causes of Dubin-Johnson syndrome in children?

A gene mutation that is hereditary (passed down in families) causes Dubin-Johnson syndrome.