Pediatric hyperinsulinism
Pediatric hyperinsulinism (hy·per·in·su·lin·ism) causes abnormally high levels of insulin, the hormone that helps control blood sugar levels.
What is pediatric hyperinsulinism?
Hyperinsulinemia is a condition in which a child’s pancreas releases too much insulin, which results in hypoglycemia (low blood sugar). In most cases, hyperinsulinemia is congenital (present at birth). However, in some cases, children may develop the condition later.
Too much insulin in the blood, which leads to low blood sugar, causes problems that affect a child’s entire body. Low blood sugar can affect brain development and can lead to seizures, brain damage, coma and possibly death.
What are the signs and symptoms of Pediatric hyperinsulinism?
Confusion
Excessive hunger
Excessive fatigue
Feeding difficulty
Irritability
Lethargy (lack of energy)
Loss of consciousness
Muscle spasms
Rapid heart rate
Shaking
Weakness
What are the causes of pediatric hyperinsulinism?
In most cases, hyperinsulinemia is congenital (present at birth) and is caused by a genetic mutation during fetal development.
When hyperinsulinemia is not caused by a genetic mutation, it may be caused by:
Gestational diabetes in the mother
Lack of oxygen to the brain at birth
Large birth weight