Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome

What is Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome?

Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a disorder that affects females reproductive system. It is a congenital condition that occurs during fetal development.

• Females born with this condition have normal external genitalia, but have underdeveloped or completely missing vagina and uterus.
• Females with this condition generally do not menstruate, but they often have normal breast and pubic hair development.
• Because females with MRKH do not have a functional uterus, they cannot bear children.

What are the different types of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome?

There are two types of MRKH syndrome:

1. MRKH syndrome type 1 only affects the reproductive organs.
2. MRKH syndrome type 2 causes abnormalities in other areas of the body (such as kidneys, spine or heart), as well as the reproductive system.

What are the signs and symptoms of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome?

In many cases, this condition shows no symptoms during childhood. The main symptom of this condition is a teenaged female who hasn't begun menstruating.

What are the causes of Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome?

The causes of MRKH is unknown, but is thought to be due to genetics.