Clinical outcome and microbiome biomarkers predicting success with fiber food introduction in short bowel syndrome

SBS and non-SBS subjects cared for in the outpatient Pediatric Gi clinics and inpatient Gi floors at Children's Health/uTSW, age 4 months corrected gestational age to 17 years old. Subjects must receive less than 20% calories from oral food not containing fiber while the other 80% may be by enteral and/or parenteral feedings, and at least 20% calories from fiber-free formula taken orally or via tube. Patients will receive increasing volume of green bean puree in their formula over the course of 3 weeks and will be maintained at the final volume for up to 6 months as tolerated. Throughout their intervention, biospecimens (blood, urine and stool) will be collected along with clinical information such as symptoms.